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Know Your Cannabinoids: HHC-O

Know Your Cannabinoids: HHC-O


Are you planning on trying the newest HHC-O cannabinoid on the market? Well, you are in the right place, my friend. We have brought all the necessary information that you might need in order to effectively start your cannabis journey. Without further adom let us dive right in. 

What Is HHC-O

What Is HHC-O

HHC-O is a new cannabinoid that was recently discovered. The substance was discovered just before the popular HHC or hexahydrocannabinoid. It is okay if you do not have an idea of what HHC-O is since it is the newest addition to the hemp industry. HHC-O is a synthetic cannabinoid. 

HHC-O is primarily an acetate of HHC. While HHC is a hydrogenated version of THC. HHC is an extremely stable compound because of the hydrogen enhancement. 

HHC transforms into HHC-O when acetic anhydride is added to the compound. In fact, this is how THC-O is also made. This process enhances the overall potency of the substance to a great effect. Users say that the potency can go up to 1.5 times. 

Manufacturers use this method to enhance the overall potency of the chemical so that it can serve as a legal alternative to Delta-9 THC. 

How Does It Affect The Endocannabinoid System?

How Does It Affect the Endocannabinoid System

ECS or the Endocannabinoid System is a complex gamut of cells that has several functions. Every human being has this system inside their bodies. The endocannabinoid system regulates functions like immune response, sleep, mood, pain perception, libido, etc. Therefore, this is a very important part of the human body. The ECS also helps a human being maintain proper homeostasis via endocannabinoids, EC receptors, and enzymes. 

Cannabinoids and Endocannabinoids work on similar principles. The only difference is that the body makes the endocannabinoids, while the cannabis class of plants externally makes cannabinoids. Both the chemicals interact with the CB1 and CB2 receptors. HHC-O has a strong affinity towards the CB1 receptor. 

As soon as the HHC-O bonds with the CB1 receptor, a feeling of relaxation and euphoria washes over the body. This provides a sense of sedation and highness to the user. This is because it triggers the psychoactive effects of the body. 

Effects Of HHC-O

Effects Of HHC-O

HHC-O is a fairly psychoactive substance like the HHC. However, HHC-O has a slower reaction time than HHC. But apart from that, the effects remain mostly similar to those of HHC, THC, and THC-P. Subsequently, HHC-O has a longer duration or retention time. In other words, you will feel the effects of this substance longer than most other cannabinoids. Some of the most popular effects of HHC-O include:

  • dry mouth
  • anxiety
  • redness of the eyes
  • insomnia
  • rapid heartbeat
  • dizziness
  • Paranoia

Studies regarding HHC-O are still going on. Hence, there could be some more effects that we do not know about yet. So, do let us know if you do know or have your own experience. 

Safety & Legality

Legality and safety become a huge concern whenever we are dealing with a substance like HHC-O. As of now, the chemical is not a banned substance. If the product follows the respective guidelines, then you need not be concerned about legality. In the Czech Republic, products containing 1% HHC-O are legal. Meanwhile, in the USA, the legal amount ranges from around 0.2% to 0.3%. Therefore, if your product follows these mandates, then it is legal. 

HHC-O is a recently discovered synthetic cannabinoid. As a result, the information we have is very sparse and inconclusive. As of now, clinical trials do not show any detrimental effects of the chemical on the human body. However, this does not mean that it is absolutely safe. Some users claimed that the substance gave them a killer headache, made them nauseous, etc. Others said that it helped them concentrate better.

The best way to avoid unnecessary trouble is by sourcing the substance from a trusted vendor. Do not source your cannabinoids from back alley vendors. Always source your cannabis and cannabinoids from vetted vendors. This will help you source high-quality cannabinoids. 



How can we conclude an article about HHC-O without comparing it with HHC? In fact, understanding the differences will truly help us study and understand both of these substances closely. 


Studies have shown that HHC-O is a step up from the HHC. This means HHC-O is reportedly more potent than HHC. This is because of the extra acetic anhydride that HHC-O has. 

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If you are looking for a mild-acting cannabinoid, then you must go for HHC. However, HHC-O is more for people who are looking for something with a little more kick. But if you are a beginner, I suggest that you choose HHC over HHC-O.


As it has already been discussed, HHC-O and HHC have similar effects. However, the intensity of these effects differs greatly from one another. Furthermore, HHC-O is a slow-acting chemical. In other words, your body will take a longer time to absorb it. As a result, HHC-O remains in your bloodstream for a longer period of time. Therefore, this is perfect for people who are looking for something that is longer lasting. 

Side Effects

HHC and HHC-O are very similar in certain aspects. This means both substances have similar side effects. However, the intensity of these side effects differs. General side effects include

  • Anxiety
  • Dizziness
  • Cottonmouth
  • Increased Appetite
  • Insomnia
  • Paranoia
  • Red eyes
  • Increased heart rate


HHC and HHC-O are the newest addition to the cannabinoid family. As a result, studies providing conclusive answers on safety are sparse.

As of now, there is no data showing that the substances are harmful. However, dosages must be controlled in order to stay safe and sound. Try not to overshoot from the preferred dosage, and you will be fine. 


In summation, that was all for today. We have discussed some very important aspects regarding HHC-O and even took time to do a comparative analysis of the substance. Keep following our page for more such content related to cannabis and other similar substances.

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